Journal of Epidemiology

Volume 30, Issue 1 (January 2020)

1)Decline in Handgrip Strength From Midlife to Late-Life is Associated With Dementia in a Japanese Community: The Hisayama Study
● Greater decline in handgrip strength over 15 years from midlife to late-life was associated with higher risks of total dementia and Alzheimer's disease.
● Maintaining muscle strength into late-life is important for preventing dementia.

2) Trends in Serum Lipid Levels of a 10- and 13-Year-Old Population in Fukuroi City, Japan (2007–2017)
● We investigated trends in serum lipids from 2007 to 2017 in a population of 10- and 13-year-old children in Fukuroi City, Japan.
● No remarkable changes in the prevalence of adverse LDL-C and HDL-C levels were observed regardless age or sex, while the prevalence of high non-HDL-C increased in boys.
● Serum LDL-C and HDL-C levels slightly increased in boys and girls aged 10 years, and HDL-C levels slightly increased in girls aged 13 years.

3) Serum Pepsinogen Values in Japanese Junior High School Students With Reference to Helicobacter Pylori Infection
● Accurate infection diagnosis was pursued with both serum and urine tests.
● In the analyses, 171 H. pylori non-infected and 8 infected students were included.
● Infected students showed higher pepsinogen I and II and lower I to II ratio.
● The distributions of serum pepsinogen differed clearly from that in adults.
● In non-infected students, males showed higher pepsinogen values than females.

4) Association of Vegetable, Fruit, and Okinawan Vegetable Consumption With Incident Stroke and Coronary Heart Disease
● We aimed to elucidate associations of total Okinawan vegetable consumption as well as total fruit and vegetable consumption with risk of incident stroke and coronary heart disease among participants who lived in Okinawa Prefecture.
● Total and specific Okinawan vegetable consumption were not statistically significantly associated with risk of stroke and coronary heart disease.
● Consumption of total vegetable and fruit in Japanese residents of Okinawa was also not associated with risk of incident stroke and coronary heart disease.

5) Study Profile
The Japan Public Health Center-based Prospective Study for the Next Generation (JPHC-NEXT): Study Design and Participants
● Japan Public Health Center-based Prospective Study for the Next Generation (JPHC-NEXT) was launched in 2011 to identify risk factors for lifestyle-related disease, elucidate factors which extend healthy life expectancy, and contribute toward personalized healthcare.
● Between 2011 and 2016, a baseline survey was conducted at 16 municipalities in 7 prefectures across the country.
● We have established a population-based cohort of 115,385 persons (Response rate 44.1%), among whom 55,278 (47.9% of participants) have provided blood and urine samples.