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Association Between Introduction of the 23-valent Pneumococcal Polysaccharide Vaccine (PPSV23) and Pneumonia Incidence and Mortality Among General Older Population in Japan: A Community-based Study
Authors
Aya Sugiyama, Masaaki Kataoka, Kentaro Tokumo, Kanon Abe, Hirohito Imada, Bunlorn Sun, Golda Ataa Akuffo, Tomoyuki Akita, Shingo Fukuma, Noboru Hattori, Junko Tanaka
J-Stage
https://www.jstage.jst.go.jp/article/jea/35/5/35_JE20240285/_article/-char/en
Highlights
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This study evaluated the support project for administering the 23-valent Pneumococcal Polysaccharide Vaccine (PPSV23) to the elderly in a super-aged town in Japan, conducted from 2010 to 2015.
- A 5-year follow-up showed an incidence of 20.3 pneumonia cases per 1,000 person-years among vaccinated residents aged 65 or older.
- The interrupted time series analysis demonstrated a 25% reduction in pneumonia mortality following the introduction of the pneumococcal vaccination support project. This shift was observed as a change in mortality from a pre-project annual increase of 0.23 to a post-project annual decrease of 0.04 per 1,000 population.
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