Journal of Epidemiology

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Comparison of Instrumental Variable Methods With Continuous Exposure and Binary Outcome: A Simulation Study

Authors

Shunichiro Orihara, Atsushi Goto

J-Stage

https://www.jstage.jst.go.jp/article/jea/35/1/35_JE20230271/_article

 
 
Highlights
  • A comprehensive side-by-side comparison of different instrumental variable (IV) methods in binary outcome and continuous exposures with many IVs was performed.
  • The findings indicated that the bias associated with these methods could not be fully addressed.
  • The use of multiple IV methods (e.g., one method for primary analysis and another for sensitivity analysis) may be helpful.
Selected Result

 

 
 
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